Beneficial effects of N-acetylcysteine in treatment resistant schizophrenia.
نویسندگان
چکیده
Poor response to antipsychotics is still an important problem in the treatment of many schizophrenia patients. N-acetylcysteine (NAC) is a compound that exerts anti-oxidant and scavenging actions against reactive oxygen species. This paper reports a case of poorly responsive schizophrenia patient who improved considerably with add-on NAC 600 mg/day. The NAC might work through activating cysteine-glutamate antiporters or reducing in nitric oxide (NO) metabolites, free radicals and cytokines or through both of these mechanisms.
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ورودعنوان ژورنال:
- The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
دوره 10 4 Pt 2 شماره
صفحات -
تاریخ انتشار 2009